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Squamous cell carcinoma of buccal mucosa

MedGen UID:
83627
•Concept ID:
C0280299
•
Neoplastic Process
Synonyms: Buccal Mucosa Squamous Cell Carcinoma; buccal mucosa squamous cell carcinoma; Carcinoma of buccal mucosa; Carcinoma of cheek mucosa; SCC - Squamous cell carcinoma of buccal mucosa; SCC of Buccal Mucosa; scc of buccal mucosa; SCC of the Buccal Mucosa; scc of the buccal mucosa; Squamous Cell Carcinoma of Buccal Mucosa; squamous cell carcinoma of buccal mucosa; Squamous Cell Carcinoma of the Buccal Mucosa; squamous cell carcinoma of the buccal mucosa
SNOMED CT: Squamous cell carcinoma of buccal mucosa (254437001); Carcinoma of cheek mucosa (254437001); SCC - Squamous cell carcinoma of buccal mucosa (254437001); Carcinoma of buccal mucosa (254437001)
 
Monarch Initiative: MONDO:0021431

Definition

A squamous cell carcinoma of the oral cavity that arises from the buccal mucosa. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSquamous cell carcinoma of buccal mucosa

Professional guidelines

PubMed

Role of combined modality treatment of buccal mucosa squamous cell carcinoma.
Lee KH, Veness MJ, Pearl-Larson T, Morgans GJ
Aust Dent J 2005 Jun;50(2):108-13. doi: 10.1111/j.1834-7819.2005.tb00349.x. PMID: 16050090
Combined-modality therapy for squamous carcinoma of the buccal mucosa: treatment results and prognostic factors.
Fang FM, Leung SW, Huang CC, Liu YT, Wang CJ, Chen HC, Sun LM, Huang DT
Head Neck 1997 Sep;19(6):506-12. doi: 10.1002/(sici)1097-0347(199709)19:6<506::aid-hed8>3.0.co;2-2. PMID: 9278759

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

Recent clinical studies

Etiology

Depth of Invasion in Squamous Cell Carcinoma of Buccal Mucosa: Is Magnetic Resonance Imaging a Good Predictor of Pathological Findings?
Jayasankaran SC, Chelakkot PG, Suresh A, V SN, Thankappan K, Iyer S, Moorthy S
Gulf J Oncolog 2022 May;1(39):39-46. PMID: 35695345
Clinicopathological correlation of tumor-stroma ratio and inflammatory cell infiltrate with tumor grade and lymph node metastasis in squamous cell carcinoma of buccal mucosa and tongue in 41 cases with review of literature.
Rani P, Gupta AJ, Mehrol C, Singh M, Khurana N, Passey JC
J Cancer Res Ther 2020 Apr-Jun;16(3):445-451. doi: 10.4103/0973-1482.193113. PMID: 32719249
Squamous cell carcinoma of buccal mucosa: a 40-year review.
DeConde A, Miller ME, Palla B, Lai C, Elashoff D, Chhetri D, St John MA
Am J Otolaryngol 2012 Nov-Dec;33(6):673-7. Epub 2012 Jun 6 doi: 10.1016/j.amjoto.2012.04.006. PMID: 22681929
Good tumor control and survivals of squamous cell carcinoma of buccal mucosa treated with radical surgery with or without neck dissection in Taiwan.
Liao CT, Wang HM, Ng SH, Yen TC, Lee LY, Hsueh C, Wei FC, Chen IH, Kang CJ, Huang SF, Chang JT
Oral Oncol 2006 Sep;42(8):800-9. Epub 2006 Feb 2 doi: 10.1016/j.oraloncology.2005.11.020. PMID: 16458038
Staging of untreated squamous cell carcinoma of buccal mucosa with 18F-FDG PET: comparison with head and neck CT/MRI and histopathology.
Yen TC, Chang JT, Ng SH, Chang YC, Chan SC, Wang HM, See LC, Chen TM, Kang CJ, Wu YF, Lin KJ, Liao CT
J Nucl Med 2005 May;46(5):775-81. PMID: 15872350

Diagnosis

Depth of Invasion in Squamous Cell Carcinoma of Buccal Mucosa: Is Magnetic Resonance Imaging a Good Predictor of Pathological Findings?
Jayasankaran SC, Chelakkot PG, Suresh A, V SN, Thankappan K, Iyer S, Moorthy S
Gulf J Oncolog 2022 May;1(39):39-46. PMID: 35695345
Transcriptome profiling and pathway analysis in squamous cell carcinoma of buccal mucosa.
Patel KD, Vora HH, Trivedi TI, Patel JB, Pandya SJ, Jetly DH, Patel PS
Exp Mol Pathol 2020 Apr;113:104378. Epub 2020 Jan 11 doi: 10.1016/j.yexmp.2020.104378. PMID: 31930966
Metastasis of carcinoma of buccal mucosa to small intestine causing ileal perforation.
Deshpande SH, Kini S, Nawalkar PR, Pandya JS
BMJ Case Rep 2019 Nov 19;12(11) doi: 10.1136/bcr-2019-231449. PMID: 31748358Free PMC Article
Diagnostic Accuracy of Computed Tomography in Detecting Bone Invasion due to Squamous Cell Carcinoma of Buccal Mucosa.
Naz N, Sattar J, Ashrafi SK
J Coll Physicians Surg Pak 2018 Nov;28(11):829-833. doi: 10.29271/jcpsp.2018.11.829. PMID: 30369373
Staging of untreated squamous cell carcinoma of buccal mucosa with 18F-FDG PET: comparison with head and neck CT/MRI and histopathology.
Yen TC, Chang JT, Ng SH, Chang YC, Chan SC, Wang HM, See LC, Chen TM, Kang CJ, Wu YF, Lin KJ, Liao CT
J Nucl Med 2005 May;46(5):775-81. PMID: 15872350

Therapy

Staging of untreated squamous cell carcinoma of buccal mucosa with 18F-FDG PET: comparison with head and neck CT/MRI and histopathology.
Yen TC, Chang JT, Ng SH, Chang YC, Chan SC, Wang HM, See LC, Chen TM, Kang CJ, Wu YF, Lin KJ, Liao CT
J Nucl Med 2005 May;46(5):775-81. PMID: 15872350

Prognosis

Depth of Invasion in Squamous Cell Carcinoma of Buccal Mucosa: Is Magnetic Resonance Imaging a Good Predictor of Pathological Findings?
Jayasankaran SC, Chelakkot PG, Suresh A, V SN, Thankappan K, Iyer S, Moorthy S
Gulf J Oncolog 2022 May;1(39):39-46. PMID: 35695345
Transcriptome profiling and pathway analysis in squamous cell carcinoma of buccal mucosa.
Patel KD, Vora HH, Trivedi TI, Patel JB, Pandya SJ, Jetly DH, Patel PS
Exp Mol Pathol 2020 Apr;113:104378. Epub 2020 Jan 11 doi: 10.1016/j.yexmp.2020.104378. PMID: 31930966
Squamous cell carcinoma of buccal mucosa: a 40-year review.
DeConde A, Miller ME, Palla B, Lai C, Elashoff D, Chhetri D, St John MA
Am J Otolaryngol 2012 Nov-Dec;33(6):673-7. Epub 2012 Jun 6 doi: 10.1016/j.amjoto.2012.04.006. PMID: 22681929
Good tumor control and survivals of squamous cell carcinoma of buccal mucosa treated with radical surgery with or without neck dissection in Taiwan.
Liao CT, Wang HM, Ng SH, Yen TC, Lee LY, Hsueh C, Wei FC, Chen IH, Kang CJ, Huang SF, Chang JT
Oral Oncol 2006 Sep;42(8):800-9. Epub 2006 Feb 2 doi: 10.1016/j.oraloncology.2005.11.020. PMID: 16458038
Staging of untreated squamous cell carcinoma of buccal mucosa with 18F-FDG PET: comparison with head and neck CT/MRI and histopathology.
Yen TC, Chang JT, Ng SH, Chang YC, Chan SC, Wang HM, See LC, Chen TM, Kang CJ, Wu YF, Lin KJ, Liao CT
J Nucl Med 2005 May;46(5):775-81. PMID: 15872350

Clinical prediction guides

Depth of Invasion in Squamous Cell Carcinoma of Buccal Mucosa: Is Magnetic Resonance Imaging a Good Predictor of Pathological Findings?
Jayasankaran SC, Chelakkot PG, Suresh A, V SN, Thankappan K, Iyer S, Moorthy S
Gulf J Oncolog 2022 May;1(39):39-46. PMID: 35695345
Clinicopathological correlation of tumor-stroma ratio and inflammatory cell infiltrate with tumor grade and lymph node metastasis in squamous cell carcinoma of buccal mucosa and tongue in 41 cases with review of literature.
Rani P, Gupta AJ, Mehrol C, Singh M, Khurana N, Passey JC
J Cancer Res Ther 2020 Apr-Jun;16(3):445-451. doi: 10.4103/0973-1482.193113. PMID: 32719249
Diagnostic Accuracy of Computed Tomography in Detecting Bone Invasion due to Squamous Cell Carcinoma of Buccal Mucosa.
Naz N, Sattar J, Ashrafi SK
J Coll Physicians Surg Pak 2018 Nov;28(11):829-833. doi: 10.29271/jcpsp.2018.11.829. PMID: 30369373
Skin involvement and ipsilateral nodal metastasis as a predictor of contralateral nodal metastasis in buccal mucosa cancers.
Mair M, Nair S, Thiagarajan SK, Agrawal J, Nair D, Chaturvedi P
Indian J Cancer 2016 Jul-Sep;53(3):394-396. doi: 10.4103/0019-509X.200674. PMID: 28244467
Squamous cell carcinoma of buccal mucosa: a 40-year review.
DeConde A, Miller ME, Palla B, Lai C, Elashoff D, Chhetri D, St John MA
Am J Otolaryngol 2012 Nov-Dec;33(6):673-7. Epub 2012 Jun 6 doi: 10.1016/j.amjoto.2012.04.006. PMID: 22681929

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    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

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    Reviews

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